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ACE2 Antibody

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.

Product Specifications

Product Name Alternative

ACEH antibody; DKFZp434A014 antibody; ACE2 antibody; metalloprotease MPROT15 antibody; angiotensin-converting enzyme homolog antibody; angiotensin I converting enzyme 2 antibody; ACE-related carboxypeptidase antibody; angiotensin-converting enzyme 2 antibody

Gene Name

ACE2

Gene ID

59272

UniProt

Q9BYF1

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fragment corresponding to a region within amino acids 406 and 677 of ACE2.

Target Antigen

ACE2

Clonality

Polyclonal

Applications

WB

Purification

Antibodies were purified by antigen-affinity chromatography.

Format

Purified

Components

Supplied at Tris, 0.1M Glycine, 20% Glycerol (pH7) . 0.01% Thimerosal was added as a preservative.

Storage Conditions

Store at -20°C

Applications Notes

Western blotting: 1:500-1:3000

Isotype

Rabbit IgG

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