Anti-Mouse CD16/CD32 PE (Clone : 93)
CD16 (FcgammaRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Unlike human, the murine protein is expressed only as a transmembrane isoform. Also CD32 (FcgammaRII) is a low affinity receptor for IgG, but its affinity is lower than that of CD16. These receptors are expressed on monocytes/macrophages, NK cells, granulocytes, mast cells, dendritic cells, and B cells. Their role is to mediate adaptive immune responses through binding the antibody-antigen immunocomplexes, but their effect on the particular cell differs according to the cell type.Specificity : The rat monoclonal antibody 93 recognizes a common extracellular epitope of murine CD16 (FcgammaRIII) and CD32 (FcgammaRII), the low affinity receptors for IgG.
Product Specifications
Product Name Alternative
CD16, CD32, FcgammaRIII, FCgammaRII, FCGR3, FCGR2
Gene Name
Fcgr2, Fcgr3
Gene ID
14130
Reactivity
Mouse
Immunogen
Murine pre-B cells
Target Antigen
CD16/CD32
Clonality
Monoclonal
Clone
93
Applications
FACS
Purification
Purified by protein-A affinity chromatography
Components
0.5 mg/mLFormulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage Conditions
Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Isotype
Rat IgG2a lambda
Conjugate
PE
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