IONIS-GCCRRx (sodium)
Product Specifications
UNSPSC Description
IONIS-GCCRRx (ISIS 426115) sodium, a glucocorticoid receptor antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO)[1].
Target Antigen
Glucocorticoid Receptor
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ionis-gccrrx-sodium.html
Smiles
[IONIS-GCCRRx (sodium)]
References & Citations
[1]Lijiang Shen, et al. Mechanistic understanding for the greater sensitivity of monkeys to antisense oligonucleotide-mediated complement activation compared with humans. J Pharmacol Exp Ther. 2014 Dec;351(3):709-17. |[2]Gaurav Chikara, et al. A Narrative Review of Potential Future Antidiabetic Drugs: Should We Expect More? Indian J Clin Biochem. 2018 Apr;33(2):121-131.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-159695A/IONIS-GCCRRx-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-159695A/
Clinical Information
No Development Reported
Curated Selection
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