TIMP2 Protein (Native, Human)

Product Specifications

Abbreviation

TIMP2

Synonyms

CSC-21K, DDC8

Host

HEK 293

Tag

Native

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method

Purity

> 96 % as determined by SDS-PAGE

Bioactivity

Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate MCA-PLGL-DPA-AR-NH2 (R&D Systems, Catalog # ES001) . The IC50 value is < 4 nM.

Function

Cys27-Pro220

Molecular Weight

The recombinant human TIMP2 consists of 195 amino acids and has a predicted molecular mass of 22 kDa. It migrates as an approximately 20 kDa band in SDS-PAGE under reducing conditions.