CLDN18 Protein (N-His & C-Strep, Human)

1.Loaded Anti-Human Claudin-18.2 antibody, human IgG1 on ProA Biosensor, can bind Recombinant Human Claudin-18.2-Nanodisc (Full Length) Protein, His & Strep Tag (Cat. No. 30025-H64H-NA) with an affinity constant of 3.43 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) . 2.Immobilized Recombinant Human CLDN18.2 -Nanodisc (Full Length) Protein (His & Strep Tag) (Cat:30025-H64H-NA) at 5 μg/mL (100 μL/well) can bind Anti-Human claudin18.2 Antibody, Human IgG1, the EC50 is 10-30 ng/mL (QC tested) . 3.Anti-Claudin 18.2 (Research Grade Zolbetuximab Biosimilar) captured on CM5 chip via Anti-Human IgG Fc, can bind Recombinant Human CLDN18.2-Nanodisc (Full Length) Protein (His & Strep Tag) (Cat: 30025-H64H-NA) with an affinity constant of 86.610 nM as determined in an SPR assay (Biacore T200) (Routinely tested) .

The recombinant Human CLDN18.2-Nanodisc consists of 303 amino acids and predicts a molecular mass of 32.34 kDa. It migrates as an approximately 27.5 kDa band in SDS-PAGE under reducing conditions.