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TACSTD2 Protein (C-His, Human)

Product Specifications

Abbreviation

TACSTD2

Synonyms

EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2

Host

HEK 293

Tag

C-His

Purity

≥ 96 % as determined by SDS-PAGE. ≥ 85 % as determined by SEC-HPLC. ≥ 95 % as determined by SEC-MALS (Routinely tested) .

Bioactivity

1.Immobilized Anti-TROP2 (Research Grade Sacituzumab Biosimilar) at 2 μg/mL (100μL/well) can bind Recombinant Human TROP2 / TACSTD2 Protein (His Tag) (Cat: 10428-H08H-UE) . The protein exhibited stable performance after 21 days of storage at 37°C, as measured on Day 0, Day 7, Day 14 and Day 21. 2.Immobilized Anti-TROP2 (Research Grade Sacituzu*mab Biosimilar) at 2 μg/mL (100μL/well) can bind Recombinant Human TROP2 / TACSTD2 Protein (His Tag) (Cat: 10428-H08H-UE), the EC50 is 3-9 ng/mL (Routinely tested) . 3.Loaded Anti-TROP2 (Research Grade Datopotamab Biosimilar) on ProA Biosensor, can bind Recombinant Human TROP2 / TACSTD2 Protein (His Tag) (Cat. No. 10428-H08H-UE) with an affinity constant of 8.13 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested) .

Function

Met1-Thr274

Molecular Weight

The recombinant human TROP2 comprises 259 amino acids and has a predicted molecular mass of 29.4 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh TROP2 is approximately 42-48 kDa due to glycosylation. The molecular weight of this protein is around 37.6 kDa verified by SEC-MALS (Routinely tested) .

Species

Human

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