NOG Protein (Native, Human)

Product Specifications

Abbreviation

NOG

Synonyms

SYM1, SYNS1, SYNS1A

Host

HEK 293

Tag

Native

Endotoxin

< 10 EU per mg protein.

Purity

≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Bioactivity

Measured by its ability to inhibit BMP4-induced alkaline phosphatase production by MC3T3E1 mouse preosteoblast cells.The ED50 for this effect is 10-80 ng/mL.

Function

Met1-Cys232

Molecular Weight

The recombinant human NOG consists of 205 amino acids and predicts a molecular mass of 23.1 kDa. As a result of glycosylation, the human NOG migrates as approximately 30 kDa band in SDS-PAGE under reducing conditions.