MAC13772
MAC13772 is a potent inhibitor of the enzyme BioA (IC50=250 nM), the antepenultimate step in biotin biosynthesis. MAC13772 is a novel antibacterial compound[1].
Product Specifications
CAS Number
[4871-40-3]
Product Name Alternative
Ro 40-7591-d4,Trimethoprim 1-N-oxide,Trimethoprim 3-N-oxide
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mac13772.html
Purity
99.33
Solubility
DMSO : 17.86 mg/mL (ultrasonic)
Smiles
O=C(NN)CSC1=CC=CC=C1[N+]([O-])=O
Molecular Formula
C8H9N3O3S
Molecular Weight
227.24
Precautions
H302, H312, H315, H319, H332, H335
References & Citations
[1]Zlitni S, et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9 (12) :796-804.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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