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Bemarituzumab (FUT8-KO)

Product Specifications

UNSPSC Description

Bemarituzumab (FUT8-KO) is a FUT8 gene missing, humanized immunoglobulin G1 monoclonal antibody against FGFR2b . Bemarituzumab (FUT8-KO) lacks a core fucose in the polysaccharide portion of the Fc domain of the antibody, and results in a high affinity to human FcγRIIIa[1].

Target Antigen

FGFR; Interleukin Related

Type

Reference compound

Related Pathways

Immunology/Inflammation;Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bemarituzumab-fut8-ko.html

Smiles

[Bemarituzumab (FUT8-KO)]

References & Citations

[1]Xiang H, et al., Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer. MAbs. 2021 Jan-Dec;13(1):1981202.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99010A/Bemarituzumab-FUT8-KO-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99010A/

Clinical Information

No Development Reported

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