Bemarituzumab (FUT8-KO)
Product Specifications
UNSPSC Description
Bemarituzumab (FUT8-KO) is a FUT8 gene missing, humanized immunoglobulin G1 monoclonal antibody against FGFR2b . Bemarituzumab (FUT8-KO) lacks a core fucose in the polysaccharide portion of the Fc domain of the antibody, and results in a high affinity to human FcγRIIIa[1].
Target Antigen
FGFR; Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation;Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bemarituzumab-fut8-ko.html
Smiles
[Bemarituzumab (FUT8-KO)]
References & Citations
[1]Xiang H, et al., Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer. MAbs. 2021 Jan-Dec;13(1):1981202.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99010A/Bemarituzumab-FUT8-KO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99010A/
Clinical Information
No Development Reported
Curated Selection
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