DHODH-IN-16
Product Specifications
UNSPSC Description
DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].
Target Antigen
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dhodh-in-16.html
Smiles
O=C1C2=C(C(C(C)C)=CN1C3=C(C)C=CC=C3)C=C(N4N=C(CO)N(CC)C4=O)C(F)=C2
Molecular Weight
436.48
References & Citations
[1]Scott Kuduk, et al. Dihydroorotate dehydrogenase inhibitors. WO2020212897A1.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139189/DHODH-IN-16-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139189/DHODH-IN-16-SDS-MedChemExpress.pdf
CAS Number
2511248-11-4
Available Sizes
Curated Selection
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