Human Immune CheckPoint Antibody panel
Product Specifications
Background
This antibody panel consists of the following: ICH4029-0.1mg Pembrolizumab Biosimilar ICH4018-0.1mg Atezolizumab Biosimilar ICH4025-0.1mg Ipilimumab Biosimilar ICH5078-0.1mg Tiragolimumab Biosimilar ICH5117-0.1mg Relatlimab Biosimilar ICH5015-0.1mg Urelumab Biosimilar ICH5079-0.1mg Sabatolimab Biosimilar (if selected) ICH5800-0.1mg Ragifilimab Biosimilar (if selected)
Reactivity
Human
Target
PD-1, PD-L1, CTLA-4, TIGIT, LAG-3, 4-1BB as standard plus TIM-3 and GITR if selected
Applications
Functional Assays
Purification Method
All the monoclonal antibodies in this panel were purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
>1.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Fragment
Human IgG4 kappa (pembrolizumab), Human IgG1 Kappa (atezolizumab), Human IgG1 Kappa (ipilimumab), Human IgG1 (tiragolimab), Human IgG4 S228P Kappa (relatlimab), Human IgG1 (urelumab), Human IgG4 S228P Kappa (Sabatolimab), Human IgG1 (Ragifilimab)
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
These antibodies are for research use only (RUO) : they are not for diagnostic or therapeutic procedures and cannot be purchased by patients.
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