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Cadonilimab Biosimilar - Research Grade

Product Specifications

Product Name Alternative

AK-104, AK104; cytotoxic T-lymphocyte-associated protein 4, CD152; programmed cell death 1, PD1, PD-1, CD279, PDCD1

Host

CHO Cells

Reactivity

Human

Target

PD-1 + CTLA-4

Sequence

https://www.imgt.org/mAb-DB/

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>90% by SDS-PAGE

Buffer

ICH3002

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Fragment

Human IgG1-kappa- (scFv - heavy - lambda2)

Specificity

Detects PD-1xCTLA-4

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

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