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Natalizumab Biosimilar - Research Grade

Product Specifications

Background

Uses the same sequence as the therapeutic antibody natalizumab

Product Name Alternative

ITGA4, CD49D, IA4, integrin subunit alpha 4

Reactivity

Human

Target

CD49d

Isotype

IgG4 κ

Sequence

https://www.imgt.org/mAb-DB/

Applications

Functional Assays

Purification Method

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration

5mg/mL

Endotoxin

<1EU/mg Determined by LAL gel clotting assay

Purity

≥95% monomer by analytical SEC, >95% by SDS Page

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Shipping Conditions

Blue ice

Storage Conditions

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Specificity

Detects human CD49d

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Applications Notes

This biosimilar is for research use only (RUO) : it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Isotype Control

Bulk Human IgG4 Isotype Control (IB4) [ICH2257]

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