Narsoplimab

Narsoplimab (OMS 721) is a high-affinity fully human immunoglobulin gamma 4 (IgG4) monoclonal antibody that binds MASP-2 and blocks lectin pathway activation. Narsoplimab can be used in research of hematopoietic stem-cell transplantation and SARS-CoV-2[1].

Product Specifications

CAS Number

[2108782-45-0]

Product Name Alternative

OMS 721; Anti-MASP2 Reference Antibody (narsoplimab)

UNSPSC

12352203

Target

SARS-CoV

Type

Inhibitory Antibodies

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/narsoplimab.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

[Narsoplimab]

Molecular Weight

(143.1 kDa)

References & Citations

[1]Gao T, et, al. Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation. Signal Transduct Target Ther. 2022 Sep 14;7 (1) :318.