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Anti-RGS7 Antibody

Boster Bio Anti-RGS7 Antibody (Catalog# A04305) . Tested in WB, ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

RGS7; Regulator of G-protein signaling 7; RGS7

Gene Name

RGS7

UniProt

P49802

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human RGS7. Immunogen sequence location: 155 - 204

Clonality

Polyclonal

Applications

WB, ELISA, IHC

Field of Research

G Protein Signaling, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767) . The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509) . May play a role in synaptic vesicle exocytosis (PubMed:12659861) . Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264) .

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

57668 MW

Gene Name Synonym

Regulator of G-protein signaling 7

Subcellular Location

Cytoplasm, cytosol.Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Interaction with PKD1 promotes location at the cell membrane (PubMed:10339594) . Interaction with RGS7BP promotes location at the cell membrane (PubMed:15897264) .

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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