Anti-FBXO7 Antibody
Boster Bio Anti-FBXO7 Antibody catalog # A04086. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
F-box only protein 7; FBXO7; FBX7
Gene Name
FBXO7
UniProt
Q9Y3I1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide from human protein at AA range: 371-420
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
58503 MW
Gene Name Synonym
F-box only protein 7
Subcellular Location
Cytoplasm. Nucleus. Mitochondrion. Cytoplasm, cytosol. Predominantly cytoplasmic. A minor proportion is detected in the nucleus. Relocates from the cytosol to depolarized mitochondria.
Contents
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
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