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Mps-BAY1

Mps-BAY1 is an MPS1 inhibitor with anticancer activity. Mps-BAY1 inhibits cell proliferation and induces apoptosis by activating mitotic catastrophe in cancer cells, generating global aneuploidy and polyploidy. Mps-BAY1 can be used in the study of colorectal cancer and cervical cancer[1].

Product Specifications

CAS Number

[1309593-24-5]

UNSPSC

12352005

Target

Apoptosis; Mitosis; Mps1

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mps-bay1.html

Smiles

N#CC1=C(NC2=NN3C=C(C4=CC=C(NC(CC5=CC=CC=C5)=O)C=C4)C=CC3=N2)C=CC=C1

Molecular Formula

C27H20N6O

Molecular Weight

444.49

References & Citations

[1]Jemaa, et al. "Characterization of novel MPS1 inhibitors with preclinical anticancer activity." Cell Death & Differentiation 20.11 (2013) : 1532-1545.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-164501/Mps-BAY1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-164501/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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