ABT-518

ABT-518 is a matrix metalloproteinase inhibitor with anti-tumor activity. ABT-518 has potent inhibitory effects on gelatinase A and gelatinase B, which can inhibit tumor growth and metastasis[1].

Product Specifications

CAS Number

[286845-00-9]

UNSPSC

12352005

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/abt-518.html

Smiles

O=CN([C@@H]([C@@H]1OC(C)(C)OC1)CS(=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O)O

Molecular Formula

C21H22F3NO8S

Molecular Weight

505.46

References & Citations

[1]Chang S J, et al. The development of a large-scale synthesis of matrix metalloproteinase inhibitor, ABT-518[J]. Organic process research & development, 2002, 6 (3) : 329-335.