Methotrexate diethyl ester
Methotrexate diethyl ester is a potent DHFR inhibitor. Methotrexate diethyl ester can be used in the research of T.cruzi infection and leukemia[1].
Product Specifications
CAS Number
[43170-88-3]
UNSPSC
12352005
Hazard Statement
H301-H315-H319-H341-H360
Target
Dihydrofolate reductase (DHFR)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Infection
Smiles
NC1=NC(N)=NC2=C1N=C(CN(C3=CC=C(C=C3)C(N[C@H](C(OCC)=O)CCC(OCC)=O)=O)C)C=N2
Molecular Formula
C24H30N8O5
Molecular Weight
510.55
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501
References & Citations
[1]McCormack JJ. Dihydrofolate reductase inhibitors as potential drugs. Med Res Rev. 1981 Fall;1 (3) :303-31.
Shipping Conditions
Room temperature
Scientific Category
Reference compound
Clinical Information
No Development Reported
Curated Selection
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