Thalidomide-O-C4-N3
Thalidomide-O-C4-N3 is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
Product Specifications
CAS Number
[2467425-50-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[N-]=[N+]=NCCCCOC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3
Molecular Formula
C17H17N5O5
Molecular Weight
371.35
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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