CPDT

CPDT is an orally active and highly potent inducer of phase 2 enzymes and an activator of Nrf2. The activities of key phase 2 enzymes, including glutathione S-transferase, NAD (P) H:quinone:oxidoreductase 1 and glutamate cysteine synthetase, and levels of glutathione were elevated by CPDT in rat bladder in vivo and in cultured bladder cells in vitro[1][2].

Product Specifications

CAS Number

[14085-33-7]

UNSPSC

12352005

Hazard Statement

H301-H412

Target

Keap1-Nrf2

Related Pathways

NF-κB

Field of Research

Neurological Disease

Smiles

S=C1SSC2=C1CCC2

Molecular Formula

C6H6S3

Molecular Weight

174.31

Precautions

P264-P270-P273-P330-P405-P501

References & Citations

[1]Xiao-Yun Liu, et al. Neuroprotective effect of CPDT on THA-induced cortical motor neuron death in an organotypic culture model. Brain Res Bull. 2010 Nov 20;83 (6) :345-50. |[2]Joseph D Paonessa, et al. 5,6-Dihydrocyclopenta[c][1,2]-dithiole-3 (4H) -thione is a promising cancer chemopreventive agent in the urinary bladder. Chem Biol Interact. 2009 Jun 15;180 (1) :119-26.