Moniliphenone

Moniliphenone (Compounds 5) is a secondary metabolite. Moniliphenone can be isolated from the endophytic fungus Penicillium chrysogenum. Moniliphenone has an anti-inflammatory activity and significantly inhibits TNF-α-stimulated NF-κB activation[1][2].

Product Specifications

CAS Number

[104022-80-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite; NF-κB

Related Pathways

Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology

Smiles

O=C(C(C(O)=CC(C)=C1)=C1O)C(C(O)=CC=C2)=C2C(OC)=O

Molecular Formula

C16H14O6

Molecular Weight

302.28

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Lin J, et al. Two new polyketides from the ascomycete fungus Leptosphaeria sp. J Antibiot (Tokyo) . 2017 Jun;70 (6) :743-746.|[2]Liu SY, et al. Isolation and characterization of two new chroman-4-ones from the endophytic fungus Penicillium chrysogenum obtained from Eucommia ulmoides Oliver. Nat Prod Res. 2022 Jul;36 (13) :3297-3302.