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PMO-G

PMO-G is a spherical-shape polymeric micelles. PMO-G has skin permeation. PMO-G can result in up to a 50-fold higher level of dystrophin in abdominal muscles of mdx mice. PMO-G can be studied in research on Duchenne muscular dystrophy[1][2].

Product Specifications

CAS Number

[2708274-72-8]

UNSPSC

12352005

Hazard Statement

H302, H314

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Metabolic Disease

Purity

99.62

Smiles

CN(C)P(OC[C@H](C1)O[C@@H](N2C3=NC(NC(C(C)C)=O)=NC(OCCC4=CC=C(C=C4)[N+]([O-])=O)=C3N=C2)CN1C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)(Cl)=O

Molecular Formula

C43H46ClN8O7P

Molecular Weight

853.30

Precautions

H302, H314

References & Citations

[1]An, J. Y., et al., (2020) . Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy. Nanoscale research letters, 15 (1), 133.|[2]Lin, C., et al., (2020) . Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle. Molecular therapy : the journal of the American Society of Gene Therapy, 28 (5), 1339–1358.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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