Suptopin-2
Sutopin-2 is a topoisomerase II inhibitor. Suptopin-2 affects cell cycle progression and stability of microtubules. Sutopin-2 induces cell cycle arrest by regulating the nucleocytoplasmic transport of cyclin B1[1].
Product Specifications
CAS Number
[331852-66-5]
UNSPSC
12352005
Target
Topoisomerase
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1OC(C)=CC(O)=C1C(/C=C/C2=CC(OC)=C(O)C(OC)=C2)=O
Molecular Formula
C17H16O7
Molecular Weight
332.30
References & Citations
[1]Haggarty SJ, et al. Small molecule modulation of the human chromatid decatenation checkpoint. Chem Biol. 2003;10 (12) :1267-1279.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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