EC 313

EC 313 is a novel selective progesterone receptor modulator. EC 313 can dose dependently reduce the weight of fibroids. EC 313 can reduce the expression of ER and PR. EC 313 can be used for the study of uterine fibroids[1].

Product Specifications

CAS Number

[1249398-29-5]

UNSPSC

12352005

Target

Estrogen Receptor/ERR; Progesterone Receptor

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Endocrinology

Smiles

C[C@@]12[C@@]3(CC[C@@]1([H])[C@@]4([H])C([C@@H](C5=CC=C(C6=COC=C6)C=C5)C2)=C7C(CC4)=CC(CC7)=O)/C(CCO3)=C(F)/F

Molecular Formula

C32H32F2O3

Molecular Weight

502.59

References & Citations

[1]Nair HB, et al. EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model. Sci Rep. 2019 Nov 21;9 (1) :17279.