Propofol-d14

Propofol-d14 (2,6-Diisopropylphenol-d14) is the deuterium labeled Propofol (HY-B0649) . Propofol potently and directly activates GABAA receptor and inhibits glutamate receptor mediated excitatory synaptic transmission. Propofol has antinociceptive properties and is used for sedation and hypnotic[1].

Product Specifications

CAS Number

[2514564-65-7]

Product Name Alternative

2,6-Diisopropylphenol-d14

UNSPSC

12352005

Target

Endogenous Metabolite; GABA Receptor; Isotope-Labeled Compounds

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

OC1=C(C=CC=C1C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H]

Molecular Formula

C12H4D14O

Molecular Weight

192.36

References & Citations

[1]R Nadeson, et al. Antinociceptive Properties of Propofol: Involvement of Spinal Cord Gamma-Aminobutyric acid (A) Receptors. J Pharmacol Exp Ther . 1997 Sep;282 (3) :1181-6.