Cloranolol
Cloranolol is an orally active nonselective β-adrenoceptor blocker. Cloranolol can reduce the content of cytochrome P-450 in rat hepatocytes, prolong hexobarbital anesthesia time, and inhibit aminopyrine-N-demethylation activity. Cloranolol can be used in the research of cardiovascular diseases such as hypertension[1].
Product Specifications
CAS Number
[39563-28-5]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor; Cytochrome P450
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
90.000000
Smiles
ClC1=CC=C(C(OCC(CNC(C)(C)C)O)=C1)Cl
Molecular Formula
C13H19Cl2NO2
Molecular Weight
292.20
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Kulcsár-Gergely J. Action of beta-adrenoceptor blockers on liver function of rats. Arzneimittelforschung. 1989 Jul;39 (7) :782-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
β adrenergic receptor
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