(Rac) -7-Ethyl-10-hydroxycamptothecin
(Rac) -7-Ethyl-10-hydroxycamptothecin is the derivative of (±) -10-Hydroxycamptothecin (HY-N0275) . (±) -10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity[1].
Product Specifications
CAS Number
[130144-34-2]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Drug Derivative; Topoisomerase
Related Pathways
Cell Cycle/DNA Damage; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CCC1=C2CN3C(C2=NC4=CC=C(C=C14)O)=CC5=C(C3=O)COC(C5(CC)O)=O
Molecular Formula
C22H20N2O5
Molecular Weight
392.40
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Wang Xuekun, et al. Camptothecin derivatives and uses thereof. CN111018897A. 2020-04-17.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Topo I
Curated Selection
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