3-Methylguanine

3-Methylguanine is a DNA damage product caused by alkylation. 3-Methylguanine is cytotoxic and causes cell death by inhibiting DNA replication. 3-Methylguanine can be used to study the mechanism of DNA damage caused by alkylating agents and its repair pathways[1].

Product Specifications

CAS Number

[2958-98-7]

Product Name Alternative

3-MG

UNSPSC

12352005

Hazard Statement

H302-H319

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Purity

90.000000

Smiles

O=C1N=C(N(C)C2=C1NC=N2)N

Molecular Formula

C6H7N5O

Molecular Weight

165.15

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Bjelland S, et al. Excision of 3-methylguanine from alkylated DNA by 3-methyladenine DNA glycosylase I of Escherichia coli. Nucleic Acids Res. 1993 May 11;21 (9) :2045-9.