Miboplatin

Miboplatin (DWA-2114R), a platinum compound, is a DNA synthesis inhibitor. Miboplatin reduces its template activity for prokaryotic and eukaryotic DNA polymerases[1].

Product Specifications

CAS Number

[103775-75-3]

Product Name Alternative

DWA-2114R

UNSPSC

12352300

Hazard Statement

H302-H315-H319-H335

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1[O-][Pt+2]2([NH2]C[C@@]3([H])CCC[NH]32)[O-]C(C14CCC4)=O

Molecular Formula

C11H18N2O4Pt

Molecular Weight

437.36

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Iwata M, et al. Sequence-dependent termination of mammalian DNA polymerase reaction by a new platinum compound, (-) - (R) -2-aminomethylpyrrolidine (1,1-cyclobutane-dicarboxylato) -2-plati num (II) monohydrate) . Jpn J Cancer Res. 1991 Apr;82 (4) :433-9.