SSR180575

SSR180575 is a specific and potent peripheral benzodiazepine receptor ligand. SSR180575 irreversibly and specifically binds with high affinity on rat heart mitochondria (Kd = 1.95 nM) . SSR180575 can be used in the research of cardiovascular diseases[1].

Product Specifications

CAS Number

[220448-02-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

GABA Receptor; Mitochondrial Metabolism

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Cardiovascular Disease

Smiles

CN1C2=C(C=CC(=C2)Cl)C3=C1C(=O)N(N=C3CC(=O)N(C)C)C4=CC=CC=C4

Molecular Formula

C21H19ClN4O2

Molecular Weight

394.85

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Vin V, et al. Binding characteristics of SSR180575, a potent and selective peripheral benzodiazepine ligand. Biochem Biophys Res Commun. 2003 Oct 24;310 (3) :785-90.