Alaptide

Alaptide, a spirocyclic synthetic dipeptide and a derivative of melanocyte-stimulating hormone release-inhibiting factor (MIF), is a transdermal permeation modifier. Alaptide loaded on nanofibrous membranes accelerates the healing of skin incisions, particularly the healing of skin burns. Alaptide is a nootropic agent, that influences the dopaminergic system and increases homovanillic acid level in the striatum of rat models. Alaptide can be used for wound healing with large damaged areas and neurological diseases research[1].

Product Specifications

CAS Number

[90058-29-0]

Product Name Alternative

VUFB-15754

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Drug Derivative

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

O=C1C2(CCCC2)NC([C@@H](N1)C)=O

Molecular Formula

C9H14N2O2

Molecular Weight

182.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Mikeš P, et al. In vitro and in vivo testing of nanofibrous membranes doped with alaptide and L-arginine for wound treatment. Biomed Mater. 2020 Nov 26;15 (6) :065023. |[2]Jampílek J, et al. Alaptide as transdermal permeation modifier[M]//Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement: Modification of the Stratum Corneum. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015: 115-132.