Antitumor agent-202
Antitumor agent-202 is a stabilizer of the p53 Y220C mutant. It exhibits a selective inhibitory effect on the proliferation of tumor cells carrying the p53 Y220C mutation and can be applied to the research of cancers associated with the p53 Y220C mutation[1].
Product Specifications
CAS Number
[38470-63-2]
UNSPSC
12352005
Target
MDM-2/p53
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
C1=CC=C(C=C1)C(=O)/C=C/C2=CNC3=CC=CC=C23
Molecular Formula
C17H13NO
Molecular Weight
247.29
References & Citations
[1]Li L, et al. Design, synthesis, and activity evaluation of indole derivatives as potential stabilizers for p53 Y220C. Bioorg Med Chem Lett. 2025 Jun 1;121:130161.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Curated Selection
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