PIM-35

PIM-35 is a derivative of Indole (HY-W001132) . PIM-35 significantly inhibits serotonin (5HT) and dopamine (DA) uptake with a weak inhibitory effect on noradrenaline (NA) uptake.PIM-35 has antidepressant activity and can be used for depression research[1].

Product Specifications

CAS Number

[130445-55-5]

UNSPSC

12352005

Hazard Statement

H302-H319

Target

5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Drug Derivative

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

COC1=CC2=C(C=C1)NC(=C2)CN

Molecular Formula

C10H12N2O

Molecular Weight

176.22

Precautions

P264-P270-P280-P330-P501

References & Citations

[1]Carranza Gómez-Carpintero MC, et al. Involvement of the serotonergic system in the mode of action of the new potential antidepressant agent 5-methoxyindolyl-2-methylamine. Arzneimittelforschung. 1993 Aug;43 (8) :809-13.