Decanoic acid-13C

Decanoic acid-13C is the 13C-labeled Decanoic acid (HY-W015309) . Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy[1][2][3].

Product Specifications

CAS Number

[84600-66-8]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

C-Met/HGFR; Glutaminase; iGluR; Isotope-Labeled Compounds; Tyrosinase

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Purity

99.30

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCC[13C](O)=O

Molecular Formula

C9 13CH20O2

Molecular Weight

173.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Boison D, et, al. New insights into the mechanisms of the ketogenic diet. Curr Opin Neurol. 2017 Apr;30 (2) :187-192.|[2]Warren EC, et al. Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling[J]. Proc Natl Acad Sci U S A. 2020 Sep 22;117 (38) :23617-23625.|[3]Yang MH, et al. Decanoic Acid Exerts Its Anti-Tumor Effects via Targeting c-Met Signaling Cascades in Hepatocellular Carcinoma Model[J]. Cancers (Basel) . 2023 Sep 22;15 (19) :4681.