Acoramone

Acoramone (2,4,5-Trimethoxyphenylacetone) is a natural product that can be isolated from phenylpropane. Acoramone is one of the main metabolites identified in the 1H NMR spectrum of fraction b of the supernatant from the incubation of liver microsomes from Aroclor 1254-pretreated rats[1][2].

Product Specifications

CAS Number

[2020-90-8]

Product Name Alternative

2,4,5-Trimethoxyphenylacetone

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

O=C(CC1=CC(OC)=C(C=C1OC)OC)C

Molecular Formula

C12H16O4

Molecular Weight

224.25

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Amarendra Patra and Alok K. Mitra, Constituents of Acorus calamus: Structure of Acoramone. Carbon-13 NMR Spectra of Cis- and Trans-Asarone. J. Nat. Prod. 1981, 44, 6, 668–669.|[2]Alexander T. Cartus, et al., Hepatic Metabolism of Carcinogenic β-Asarone. Chem. Res. Toxicol. 2015, 28, 9, 1760–1773.