Sulfabenz
Sulfabenz (Compound 9) is an amine-substituted N1-phenylsulfonyl indole derivative. Sulfabenz has binding activity to human 5-HT6 serotonin receptor (Ki: 200 nM) . Sulfabenz can be used to study the ligand binding mechanism of 5-HT6 receptor and 5-HT6 receptor-related neurological diseases[1].
Product Specifications
CAS Number
[127-77-5]
UNSPSC
12352005
Hazard Statement
H227, H301
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
95.00
Smiles
C1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)N
Molecular Formula
C12H12N2O2S
Molecular Weight
248.31
Precautions
H227, H301
References & Citations
[1]Pullagurla M, et al. Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors. Bioorg Med Chem Lett. 2005 Dec 1;15 (23) :5298-302.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT6 Receptor
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