STAT6-IN-7
STAT6-IN-7 (Compound 178) is a STAT6 inhibitor. STAT6-IN-7 has an IC50 value for inhibiting the binding of human STAT6/pIL-4Rα of 0.28 μM. STAT6-IN-7 can be used in the research of inflammatory and allergic diseases[1].
Product Specifications
CAS Number
[3033743-58-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related; STAT
Related Pathways
Immunology/Inflammation; JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Purity
99.88
Smiles
O=C(C1=CC(NC(C2=CC(C(F)(F)F)=CC3=C2N(CCOC)C(C4=CC=C(N5C(N(C)N=C5C)=O)C=C4)=C3)=O)=CC=C1)NC6=NN(C7CC7)C=C6
Molecular Formula
C36H33F3N8O4
Molecular Weight
698.69
Precautions
H302, H315, H319, H335
References & Citations
[1]YAMAMOTO, et al. Fused ring compound and pharmaceutical containing same. WO2024071439A1. 2024-04-04.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
IL-4; STAT6
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