PEG5000-C-DMG

PEG5000-C-DMG is a PEGylated derivative of 1,2-Dimyristoyl-sn-glycerol (HY-128468) . PEG5000-C-DMG can be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of siRNA[1].

Product Specifications

CAS Number

[1443687-74-8]

UNSPSC

12352200

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

CCCCCCCCCCCCCC(OC(COC(NCCCOCCOC)=O)COC(CCCCCCCCCCCCC)=O)=O.[n]

Molecular Formula

(C2H4O) nC36H69NO7

Molecular Weight

5000 (average)

References & Citations

[1]Hobo W, et al. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation. Cancer Immunol Immunother. 2013 Feb;62 (2) :285-97.