Boc-12-Ado-OH
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Product Specifications
CAS Number
[18934-81-1]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
PROTAC Linkers
Related Pathways
PROTAC
Field of Research
Cancer
Purity
98.0
Smiles
CC(OC(NCCCCCCCCCCCC(O)=O)=O)(C)C
Molecular Formula
C17H33NO4
Molecular Weight
315.45
Precautions
H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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