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α-FMH

α-FMH (α-Fluoromethylhistidine) is a potent histidine decarboxylase (HD) inhibitor used in studies to reduce histamine levels[1].

Product Specifications

CAS Number

[73804-75-8]

Product Name Alternative

α-Fluoromethylhistidine

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Amino Acid Decarboxylase

Related Pathways

Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Smiles

OC([C@@](CF)(N)CC1=CN=CN1)=O

Molecular Formula

C7H10FN3O2

Molecular Weight

187.17

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Garbarg M, et al. Inhibition of histamine synthesis in brain by alpha-fluoromethylhistidine, a new irreversible inhibitor: in vitro and in vivo studies. J Neurochem. 1980 Nov;35 (5) :1045-52.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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