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2-Bromo-4'-fluoroacetophenone

2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.

Product Specifications

CAS Number

[403-29-2]

Product Name Alternative

P-Fluorophenacyl bromide

UNSPSC

12352005

Hazard Statement

H314

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

99.29

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

BrCC(C1=CC=C(F)C=C1)=O

Molecular Formula

C8H6BrFO

Molecular Weight

217.04

Precautions

H314

References & Citations

[1]Wender P A, et al. Photoinduced cleavage of DNA by bromofluoroacetophenone–pyrrolecarboxamide conjugates[J]. Bioorganic & medicinal chemistry letters, 2003, 13 (10) : 1763-1766.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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