2-Bromo-4'-fluoroacetophenone
2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.
Product Specifications
CAS Number
[403-29-2]
Product Name Alternative
P-Fluorophenacyl bromide
UNSPSC
12352005
Hazard Statement
H314
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
99.29
Solubility
DMSO : 66.67 mg/mL (ultrasonic)
Smiles
BrCC(C1=CC=C(F)C=C1)=O
Molecular Formula
C8H6BrFO
Molecular Weight
217.04
Precautions
H314
References & Citations
[1]Wender P A, et al. Photoinduced cleavage of DNA by bromofluoroacetophenone–pyrrolecarboxamide conjugates[J]. Bioorganic & medicinal chemistry letters, 2003, 13 (10) : 1763-1766.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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