Estradiol 3-methyl ether
Estradiol 3-methyl ether is a synthetic estrogen. Estradiol 3-methyl ether can disrupt microtubule networks in V79 cells with an EC50 of 9 μM, as well as inhibiting cell proliferation. Estradiol 3-methyl ether decreases the serum cholesterol levels and increases body weight loss, which indicates feminizing activity in HFD murine model[1][2].
Product Specifications
CAS Number
[1035-77-4]
Product Name Alternative
3-O-Methyl estradiol; 17β-Estradiol 3-methyl ether; 3-Methoxyestradiol
UNSPSC
12352211
Hazard Statement
H302+H312+H332
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Endocrinology
Purity
99.93
Smiles
C[C@]12CC[C@]3([H])C4=CC=C(OC)C=C4CC[C@@]3([H])[C@]1([H])CC[C@]2([H])O
Molecular Formula
C19H26O2
Molecular Weight
286.41
Precautions
H302+H312+H332
References & Citations
[1]Aizu-Yokota, E., et al., (1995) . Natural estrogens induce modulation of microtubules in Chinese hamster V79 cells in culture. Cancer research, 55 (9), 1863–1868. |[2]R.M. Tomarelli, et al., Bioassay of Hypocholesterolemic Steroids, Journal of Pharmaceutical Sciences, Volume 55, Issue 12, 1966.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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