4-Methylthiazole
4-Methylthiazole is an Apoptosis trigger. 4-Methylthiazole markedly reduces CD45 and CD123 surface markers, increases ROS levels, Caspase-3 protein levels. 4-Methylthiazole triggers Apoptosis and mitochondrial disruption. 4-Methylthiazole can be used in the research of acute promyelocytic leukemia[1].
Product Specifications
CAS Number
[693-95-8]
UNSPSC
12352200
Hazard Statement
H226, H302, H315, H318, H335
Target
Apoptosis; Caspase; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.96
Solubility
10 mM in DMSO
Smiles
CC1=CSC=N1
Molecular Formula
C4H5NS
Molecular Weight
99.15
Precautions
H226, H302, H315, H318, H335
References & Citations
[1]Meriç N, et al. 4-Methylthiazole triggers apoptosis and mitochondrial disruption in HL-60 cells. Mol Biol Rep. 2024 Sep 19;51 (1) :997.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
Caspase 3
Available Sizes
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