PNT2001
PNT2001 (LY4181530) is a potent prostate specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. PNT2001 can improve cellular internalization. 177Lu- and 225Ac-labeled PNT2001 can be used in prostate cancer research[1].
Product Specifications
CAS Number
[2790413-59-9]
Product Name Alternative
LY4181530; PSMA-62
UNSPSC
12352209
Target
PSMA
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Purity
98.72
Solubility
DMSO : 50 mg/mL
Smiles
OC(C=C1)=CC=C1C[C@@H](NC([C@@H](NC(CC[C@@H](N2CCN(CCN(CCN(CC2)CC(O)=O)CC(O)=O)CC(O)=O)C(O)=O)=O)CC3=CC=C(C=C3)N)=O)C(N[C@@H](C(N[C@@H](C(O)=O)CCCCNC([C@@H](CC(NCCC[C@H](C(O)=O)NC(CC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)NC(C4=CC(C(O)=O)=CC(C(O)=O)=C4)=O)=O)=O)CC5=CC6=C(C=CC=C6)C=C5)=O
Molecular Formula
C85H107N15O32
Molecular Weight
1850.84
References & Citations
[1]A. Vito1, et al. Development and characterization of 225Ac-PNT2001, a next-generation PSMA radioligand.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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