Daeatal

Daeatal (Dynorphin A ethylamide (1-9) ) is an ethylamine-modified dynorphin fragment that can be used in the study of analgesia, addiction, depression, etc. Dynorphin A is an endogenous opioid peptide involved in inhibitory neurotransmission in the central nervous system (CNS) . Dynorphin A is a highy potent kappa opioid receptor (KOR) agonist, and is also an agonist for other opioid receptors, such as mu (MOR) and delta (DOR) . Dynorphin A can induce neuronal death, and can be used in the research of neurological disease[1].

Product Specifications

CAS Number

[103614-28-4]

Product Name Alternative

Dynorphin A ethylamide (1-9)

UNSPSC

12352209

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

OC(C=C1)=CC=C1C[C@H](NC)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N(C)[C@@H](CCCNC(N)=N)C(N[C@H](CC(C)C)C(N[C@H](C(NCC)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C56H93N19O10

Molecular Weight

1192.46

References & Citations

[1]Hauser KF, et al. Dynorphin A (1-13) neurotoxicity in vitro: opioid and non-opioid mechanisms in mouse spinal cord neurons. Exp Neurol. 1999 Dec;160 (2) :361-75.