Bradykinin (1-5) (TFA)
Bradykinin (1-5) (TFA) is a major stable metabolite of Bradykinin (HY-P0206), formed by the proteolytic action of angiotensin-converting enzyme (ACE) . Bradykinin (1-5) (TFA) inhibits α- and γ-thrombin-induced platelet aggregation[1].
Product Specifications
UNSPSC
12352209
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
N=C(NCCC[C@@H](C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)N)N.OC(C(F)(F)F)=O.[x]
Molecular Formula
C27H40N8O6.xHC2O2F3
Molecular Weight
572.66 (free base)
References & Citations
[1]Murphey LJ, et al. Bradykinin and its metabolite Bradykinin 1-5 inhibit thrombin-induced platelet aggregation in humans. J Pharmacol Exp Ther. 2006 Sep;318 (3) :1287-92.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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