MNLS-CPP-WSTF (TFA)
MNLS-CPP-WSTF TFA is the trifluoroacetate salt of mNLS-CPP-WSTF (HY-P11208) . mNLS-CPP-WSTF is a nuclear localization signal (NLS) -cell-penetrating peptide based on the mouse WSTF sequence. mNLS-CPP-WSTF significantly inhibits the GABARAP-WSTF interaction, WSTF degradation and inflammatory gene expression. mNLS-CPP-WSTF effectively attenuates chronic inflammation, liver fibrosis and cartilage damage in metabolic-dysfunction-associated steatohepatitis (MASH) and osteoarthritis (OA) mice model. mNLS-CPP-WSTF is promising for research of chronic inflammatory diseases such as MASH and OA[1].
Product Specifications
UNSPSC
12352209
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Inflammation/Immunology
Purity
96.20
Smiles
Molecular Formula
C219H361N69O64.xC2HF3O2
Molecular Weight
4984.63 (free base)
References & Citations
[1]Wang Y, et al. WSTF nuclear autophagy regulates chronic but not acute inflammation. Nature. 2025 Jul 2.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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