Gymnin

Gymnin is a defensin-like antifungal peptide. Gymnin has significant antifungal activities against phytopathogenic and mycotoxigenic fungi. Gymnin inhibits HIV-1 reverse transcriptase with an IC50 of 200 μM and the proliferation of tumor cells. Gymnin has a weak mitogenic activity toward murine splenocytes. Gymnin can be used for plant disease treatments research[1][2].

Product Specifications

CAS Number

[1427515-26-1]

UNSPSC

12352209

Target

Fungal; HIV; Reverse Transcriptase

Related Pathways

Anti-infection

Field of Research

Cancer; Infection

Smiles

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=C(C=C1)O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

Molecular Formula

C48H74N12O20S

Molecular Weight

1171.23

References & Citations

[1]Wong JH, et al. Gymnin, a potent defensin-like antifungal peptide from the Yunnan bean (Gymnocladus chinensis Baill) . Peptides. 2003 Jul;24 (7) :963-8. |[2]Leannec-Rialland V, et al. Use of Defensins to Develop Eco-Friendly Alternatives to Synthetic Fungicides to Control Phytopathogenic Fungi and Their Mycotoxins. J Fungi (Basel) . 2022 Feb 25;8 (3) :229.