FNIII14

FNIII14 is derived from the 14th fibronectin (FN) type III-like (FN-III) repeat of FN molecule. FNIII14 is capable of inhibiting cell adhesion to the extracellular matrix (ECM) . FNIII14 induces a conformational change in β1-integrin from the active to the inactive form, and blocks integrin-mediated signaling. FNIII14 has anti-fibrotic, anti-cancer effect. FNIII14 can be used for research of metabolic diseases, organ fibrosis, and malignant tumors[1].

Product Specifications

CAS Number

[206536-96-1]

UNSPSC

12352209

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Smiles

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